Meclizine has antihistaminic and anticholinergic properties. It is used for the prevention and symptomatic treatment of nausea, vomiting and dizziness.
It is a nonsteroidal anti-inflammatory agent that effectively inhibits the synthesis of prostaglandins, has antipyretic, anti-inflammatory and analgesic effects. In addition, it reversibly inhibits collagen-induced platelet aggregation. In oral administration, the drug is partly absorbed in the abdomen and then completely in the intestine. After metabolism in the liver (hydroxylation, carboxylation) pharmacologically inactive metabolites are completely excreted in the urine. In oral administration, the maximum concentration in blood plasma is achieved in 1-2 hours.
Anticholinesterase agent; having a cholinesterase effect through a reversible acetylcholinesterase inhibition and enhancing the action of acetylcholine. Improves neuromuscular transmission, increases the motility of the gastrointestinal tract, increases the tone of urinary bladder, bronchi, the secretion of exocrine glands. Prescribed for myasthenia gravis, postoperative intestinal atony, atonic constipation, bladder atony, post-traumatic movement disorders; flaccid paralysis; residual explication of polio, encephalitis, violation of emptying the bladder after gynecological surgery and childbirth.
Mentat improves mental functions by modulating cholinergic neurotransmission and by restoring the activity of the frontal cortical muscarinic and cholinergic receptors. It improves mental activity, memory duration, concentration ability, reduces tension and increases the detention to stress. The drug is aimed to lower the level of tribulin. It also improves the quality of attention and stabilizes behavioral reactions. Mentat provides important assistance in Parkinson's disease. Mentat improves articulation and corrects speech defects. It promotes the mental development of children.
An antituberculosis drug which acts bacteriostatically; it enters the actively growing cells of mycobacteria by inhibiting RNA synthesis, interferes with cellular metabolism, causing cessation of reproduction and death of bacteria. Active only in relation to the intensively dividing cells. Inhibits the growth and reproduction of tuberculosis mycobacterium resistant to streptomycin, isoniazid, PASK, ethionamide, kanamycin. In the conditions of monotherapy, the resistance of mycobacteria develops fast enough.
Coumadin - anticoagulant of indirect action. It is taken for treatment and prevention of a deep vein thrombosis and embolism of a pulmonary artery, the transitory ischaemic attacks and an ischemic stroke, secondary prevention of myocardial infarction and prevention of tromboembolic episodes after a myocardial infarction, prevention of tromboembolic episodes at patients with fibrillation of auricles, cardiac valve damage or with the fitted prosthesis heart valves.
