Antibiotic with antitumor activity obtained from the Streptomyces caespitosus fungus. It inhibits DNA synthesis, in high concentrations it inhibits the synthesis of protein and RNA. Has a relatively weak immunosuppressive activity.
The drug therapeutic indications include: esophageal cancer, stomach cancer, pancreatic cancer, liver cancer, cancer of the bile ducts, cancer of the colon and rectum, breast cancer, cervical cancer, endometrial cancer, vulvar cancer, non-small cell lung cancer, mesothelioma, cancer of the renal pelvis and ureter, bladder cancer, prostate cancer, malignant tumors of the head and neck, chronic myelocytic leukemia.