Antabuse - the medicine for treatment of alcoholism. The effect of medicine is implemented due to blockade of acetaldehydehydrogenaz which takes part in ethanol metabolism in consequence of which rises the level of acetaldehyde which causes a number of negative symptoms (including hot flashes, hyperemia of face, vomiting, tachycardia and increase in pressure). These effects arising after alcohol intake lead to development of cause-effect relations and rejections of alcohol intake. Thus, the patient has a conditioned-reflex disgust for a smell and taste of alcohol.