Zoloft is an antidepresant stopping the reuptake of serotonin, which is performed by the neurons that isolated it. As a result, the concentration of the neurotransmitter increases in the synaptic cleft and the main cause of depressive states, the serotonin deficiency, is eliminated.

Anti-migraine drug. Specific and selective agonist of 5-HT1-serotonin receptors, localized predominantly in the blood vessels of the brain and it does not affect other subtypes of 5-HT-serotonin receptors (5-HT2-7). Causes narrowing of the vessels of the carotid arterial bed, that supply extracranial and intracranial tissues with blood (vasodilation of the meninges and / or their edema is the main mechanism of migraine development in humans) without significantly affecting cerebral blood flow.